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Good to Know - Flights from San Francisco to Santiago

Low Season:
December
Best time to beat the crowds
High Season:
May
Most popular time to fly
Good Deal:
$ 544.21
or less (round trip)

Cheapest Day of the Month to Book Flights



Top Tips for Finding Cheap Flights from San Francisco to Santiago

Looking for cheap airfare from San Francisco to Santiago? 25% of our users found round-trip tickets to Santiago for the following price or less: $ 544.21 Book at least 4 weeks before departure in order to get a below-average price. High season is considered to be May. The cheapest month to fly from San Francisco to Santiago is December. Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Francisco to Santiago flight deals.

FAQs - Booking from San Francisco to Santiago flights

How long is the flight from San Francisco to Santiago?
A flight from San Francisco to Santiago takes 15hours.
What is the cheapest flight San Francisco to Santiago?:
The cheapest flight San Francisco to Santiago found on flyus.com in the last 72 hours was $544.21 round-trip.
 
Which airlines fly to Santiago?:
• Avianca
• Copa Airlines
• LATAM airlines group
• American Airlines
• Alaska Airlines
• United Airlines
• JetBlue Airways
• LATAM Airlines Brazil
• Qantas Airways
• British Airways
 

Find cheap flights from San Francisco to Santiago and book discounted airfare from different cities all over the United States. Explore airline ticket deals on flight routes all over the World! At Flyus, we take pride in helping you discover and book the best flight deals for your next trip at the cheapest price. We make booking flights from different departures easy and provide you with peace of mind with our Best Purchase Guarantee.

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Cheapest Flights
from San Francisco, United States (SFO) to:

  • Santiago, Chile (SCL)
    Mar 18, 25 - Mar 19, 25
    $544.21
    Search

  • Santiago, Chile (SCL)
    Feb 17, 25 - Feb 24, 25
    $662.01
    Search

  • Santiago, Chile (SCL)
    Mar 03, 25 - Mar 19, 25
    $662.01
    Search

  • Santiago, Chile (SCL)
    Mar 03, 25 - Mar 13, 25
    $662.01
    Search

  • Santiago, Chile (SCL)
    Feb 10, 25 - Feb 19, 25
    $662.01
    Search